Saturday, February 9, 2013

Is Prostaglandin D2 the cause for Male Pattern Baldness?

Would he use a drug  to
block prostaglandin d2
buildup?
As many have probably read or heard, scientists at the University of Pennsylvania published an article in Science Translational Medicine Journal which reveals that hair loss or androgenic alopecia may be linked with elevated levels of a substance known as prostaglandin D2. The results of this study might result in effective treatment for people suffering from hair loss.
The scientists discovered that during normal follicle cycling, prostaglandin D2 levels increase immediately preceding the regression phase which suggests that it has an inhibitory effect on hair growth. In addition to this, males diagnosed with androgenic alopecia are also affected by abnormal levels of prostaglandin D2 which has a tendency to constantly accumulate in areas of androgenic baldness.
Highly increased levels of prostaglandin D2 will lead to inflammation around hair follicles which eventually causes the hair to fall out. The discovery sheds light on the phenomenon (observed in androgenic alopecia patients of both sexes) of the growth of connective tissue around hair follicles - the cause of the miniaturization of hair follicles and eventual hair loss.
It is, however, to early to rule out other factors believed to cause hair loss such as DHT, but this research will hopefully result in the development of a drug beneficial to those suffering from hair loss.